Mastering Endosomal Escape for Enhanced Drug Delivery: Strategies to Ensure Efficacy, Safety, & Cytoplasmic Release
Time: 12:00 pm
day: Day One
Details:
- Identifying and incorporating efficient endosomal escape mechanisms in drug delivery systems, such as peptides or polymers that can facilitate disruption of the endosomal membrane
- Study of an amphiphilic alpha-helical peptide that enables rapid cytoplasmic delivery of biomolecules such as base editor RNP and PMO
- Enhancing peptide and PMO delivery to airway epithelia by chemical conjugation with amphiphilic peptide
