David Guay

Company: Feldan Therapeutics

Job title: Vice President Innovation and Technology

Seminars:

Panel Discussion: Overcoming Endosomal Escape & Compartmentalization for Targeted Delivery 10:00 am

Tackling endosomal membrane impermeability to ensure timely drug release into the cell cytoplasm to improve drug efficacy Balancing efficacy and safety: strategies to minimize cytotoxicity in endosomal escape approaches for safer drug delivery Exploring novel technologies and formulations to enhance endosomal escape efficiency, including the use of advanced nanocarriers and membrane-disruptive agents, to optimize the…Read more

day: Day One

Mastering Endosomal Escape for Enhanced Drug Delivery: Strategies to Ensure Efficacy, Safety, & Cytoplasmic Release 12:00 pm

Identifying and incorporating efficient endosomal escape mechanisms in drug delivery systems, such as peptides or polymers that can facilitate disruption of the endosomal membrane Study of an amphiphilic alpha-helical peptide that enables rapid cytoplasmic delivery of biomolecules such as base editor RNP and PMO Enhancing peptide and PMO delivery to airway epithelia by chemical conjugation…Read more

day: Day One