INspire – A Novel Intracellular Delivery Platform for Protein-Based Therapeutics

Time: 9:35 am
day: Day One


  • The INspire intracellular delivery platform is based on conjugation of proteinbased therapeutic payloads to a chemically modified carrier protein which enables cell internalization and efficient endosomal escape
  • The INspire carrier was shown in vitro to deliver various payloads with differen functionalities and to inflict biological effects in various cancer models
  • The platform exhibited clinically relevant pharmacokinetics and biodistribution profiles as well as in vivo functionality in several oncology models