INspire – A Novel Intracellular Delivery Platform for Protein-Based Therapeutics
Time: 9:35 am
day: Day One
Details:
- The INspire intracellular delivery platform is based on conjugation of proteinbased therapeutic payloads to a chemically modified carrier protein which enables cell internalization and efficient endosomal escape
- The INspire carrier was shown in vitro to deliver various payloads with differen functionalities and to inflict biological effects in various cancer models
- The platform exhibited clinically relevant pharmacokinetics and biodistribution profiles as well as in vivo functionality in several oncology models
